What are the main preparation methods of tablets?

Generally, there are direct compression, wet granulation (most commonly used) and dry granulation.

Because wet method is used most in China, and most of them are skilled, it is generally used.

Dry granulation is only used for wet granulation, for example, raw materials are unstable to damp heat, and wet granulation cannot control its dissolution.

Direct tabletting is advocated abroad, because its preparation process is relatively simple and the error is small, but it is still relatively rare in China, because to use direct tabletting, the physical properties of raw materials must be good first, and the density should not be too large or too small. Secondly, the excipients should be directly tabletted (such as microcrystalline cellulose PH 102, etc. ), which are all imported at present.