What are that main method for preparing monoclonal antibody target preparations? What is the practical significance of monoclonal antibody targeting preparation?

Bevacizumab is widely used in monoclonal antibody targeting preparations and combined chemotherapy drugs, and its practical significance varies from person to person.

1, passive targeting preparations (liposomes, emulsions, microspheres, nanocapsules and nanospheres, etc. )

2. Active targeting agents (modified liposomes, long-circulating liposomes, immunoliposomes, etc.). )

3. Physicochemical targeting agents (magnetic targeting agents, embolic targeting agents, thermal targeting agents, PH targeting agents)

Extended data:

Targeted preparations not only require drugs to reach the lesion site, but also require a certain concentration of drugs to stay at these targets for a certain period of time to exert their efficacy. A successful targeted preparation should have four elements: location, concentration, controlled release, non-toxicity and biodegradability. Targeted preparations have been paid more and more attention by medical circles at home and abroad because they can improve the curative effect, reduce toxicity, improve the safety, effectiveness and reliability of drugs and the compliance of patients.

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