Clinical significance of Nissl bodies

Improvement of Nissl bodies staining method and its application in neuropathology research

The staining of tissues or cells is of great significance and use value in pathological diagnosis, scientific research and teaching. The quality of tissue section staining is very important for medical diagnosis, scientific research and teaching. In the traditional toluidine blue staining process, only the nucleus and Nissl bodies are considered, but the cytoplasm and other organelles are not considered. The modified toluidine blue staining method uses eosin after toluidine blue staining, which not only considers the nucleus and Nissl bodies, but also dyes the cytoplasm. The results show that the traditional toluidine blue staining results show that both the nucleus and Nissl bodies can be seen under the light microscope, that is, Nissl bodies are dark blue, the nucleus is blue and the staining background is light blue. The results of improved staining showed that Nissl bodies were purple-blue, the nucleus was blue and the staining background was pink. It can be seen that the tissue sections dyed by the improved staining method are clearer and more beautiful than the traditional staining method. With the rapid development of science and technology, pathological research has also developed, and pathological technology will be further improved to adapt to the progress of science and technology and the development of medicine. The improved Nissl's corpuscle staining method can make the observation of brain tissue sections more clear, which is more conducive to the study of nerve tissue and Nissl's corpuscle by medical workers.