Angelica dahurica efficacy and role

Angelica dahurica is a traditional Chinese medicine, has high medicinal value, so what are the effects and functions of Angelica dahurica, take a look

Effects of Angelica dahurica

Angelica dahurica, also known as Angelica dahurica. Taste pungent, warm, to the lungs, spleen, stomach, large intestine meridian. Functions of the wind to relieve the surface, dispel cold pain, remove dampness and pass through the hole, eliminate swelling and pus. Modern pharmacological studies have proved that dahurica dahurica in addition to antipyretic, analgesic, anti-inflammatory effects, but also improve local blood circulation, eliminate excessive accumulation of pigment in the tissues, and promote the metabolism of skin cells, and then to achieve the role of cosmetic, commonly used in clinics to treat wind-cold cold and flu, headache, toothache, pain in the eyebrow, nasal abyss, intestinal hemorrhoidal leakage, reddish white belt, carbuncle sores, snake bites, and so on.

The role of Angelica dahurica

Beauty

Dispel the wind and relieve epidemics, dispersing cold and pain, removing dampness, eliminating swelling and pus. It improves microcirculation, promotes skin metabolism, eliminates excessive accumulation of pigment in tissues, removes facial discoloration and scarring, and treats skin blisters and scabies. The Divine Husbandman's Classic of the Materia Medica states that Angelica dahurica: ? Long skin. Moisturize the color, can be used as facial fat.? Whether it is? Thousand gold face fat formula? or the Empress Dowager Cixi's secret formula to keep the face of the court? Yurongsan? , Angelica dahurica is the main medicine for making face cream. It is said to be able to remove dark spots on the face. Modern medicine has proved that Angelica dahurica on acne, blackheads, pimples have a certain efficacy, in whitening the spot, improve microcirculation, delay skin aging have a unique therapeutic effect.

Anti-inflammatory effect

Mice gavage Angelica dahurica or Hangzhou Angelica dahurica decoction (lg equivalent to the raw medicine lg) 4g/kg, can significantly inhibit the xylene-induced inflammation of the ear in mice (P<0.01).

Antipyretic and analgesic effect

With peptone subcutaneous injection in the back of the great white rabbit caused by hyperthermia animal model, 1g Angelica dahurica or Hangbaizhi dahuricae decoction 15g/kg, there is a significant antipyretic effect. Mice gavage Angelica dahurica or Angelica dahurica decoction 8g/kg, on the intraperitoneal injection of 1% acetic acid (0.l/kg) caused by the number of twisting of the mouse significantly reduced, the effect is similar to aminopyralid 8mg/kg, P<0.001. Mice hot plate test, the pain threshold before the administration of the drug in 30 minutes or less, gavage to give to the Angelica dahurica or Angelica dahurica 8g/kg, after the administration of the drug for 60 minutes, Angelica dahurica and anti-Dahurica dahurica On the pain threshold significantly increased, compared with saline group P & lt; 0.001 and 0.01.

Antispasmodic effect

Contained bergamot lactone, peppercorn toxin, iso-europregnanolone B on the rabbit ileum has a significant antispasmodic effect. Isoeuropregnathin also increases the contractility of the rabbit uterus and the tension of the earthworm muscle. Scopolamine has an antispasmodic effect on uterine spasm caused by estrogen or barium chloride in in vitro or isolated rats, with an ED50 of 0.09 mg/kg.

Cardiovascular effects

The iso-European prehistatin and Indian quince contained in this product have a hypotensive effect on cats, with 50 mg/kg lowering arterial blood pressure by 50%, and with an action Maintenance time is 1.5 hours. The ****polymerization of isoeuropregnanol and N-vinylpyrrolidone can prolong the `time' of arterial pressure lowering in cats by 5-10 times. It also reduces the contractility of isolated frog hearts.

Antimicrobial effect

Angelica dahurica decoction has inhibitory effect on Escherichia coli, dysentery bacillus, metaplasma, typhoid bacillus, paratyphoid bacillus, Pseudomonas aeruginosa, Vibrio cholerae, and human type tuberculosis bacillus. The product contains oxypregnanol in vitro test on 11 strains of bacteria have antibacterial effect; Europe also has antibacterial effect of prenylcystin pepper toxin; human tuberculosis mycobacterium H37RV MIC of 100mcg/ml. water immersion on the Audu ounce of small germs such as jock itch and other pathogenic fungi have a certain degree of inhibition.

Photosensitization

The furanocoumarins contained in this product, such as citrulline, peppercorn toxin and iso-Eucalyptus b, are photoreactive substances, and when they enter the organism, once irradiated by sunlight or ultraviolet radiation, they can make the irradiated place of the skin to develop solar dermatitis, which occurs as redness, swelling, pigmentation increase, and vegetative thickening of the skin. Photosensitizing activity to pepper toxin for the strongest, citrus lactone, followed by iso-europregnathin B weaker. Photosensitizers can be used to treat vitiligo. Isoeuropremarin is an active ingredient in the treatment of psoriasis, and has been clinically proven to be effective with erythema volume measurements.

Anti-cancer effects

Isoeuropregnanol and autogobilin have cytotoxic effects on Hela cells. The ED50 of isoeuropterocarpine is 100?g/ml.

Anti-radiation effects

Dahurica dahurica methanolic extract 1g/kg intraperitoneally injected 5 minutes prior to X-ray irradiation showed protective effects against skin damage in mice.

Other effects

A small amount of Angelica dahurica dahurica poison on the medulla oblongata vasomotor center, the respiratory center, the vagus nerve and the spinal cord have an excitatory effect, can make the blood pressure rise, the pulse rate slows down, deepening of the respiratory rate, and can cause salivation and vomiting, and a large number of use can cause tonic intermittent spasm, followed by generalized paralysis.

Clinical reports: modern external treatment of joint effusion, herpes zoster, psoriasis and other disorders with the product is effective.