What are the problems in the delivery of biotechnological drugs?

Toxicity problem and efficiency problem.

1, the vast majority of biotechnological drugs are endogenous substances of biological macromolecules, and the stability of these drugs is poor, so a long time in the administration process will affect the action of drugs and lead to toxicity problems.

2. Due to multiple biological obstacles in the human body, the delivery efficiency of biological drugs is very low, which not only has the problem of insufficient dose, but also easily produces great toxic and side effects.