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Preparation method of fenpropathrin

Preparation of 2,2,3,3-tetramethylcyclopropane carboxylic acid

2,3-dimethylbutene reacts with α-chloroketene to generate corresponding α-halocyclobutanone, and then 3 yuan ring is formed by Favorskii rearrangement in the presence of alkali to generate 2,2,3,3-tetramethylcyclopropane carboxylic acid.

2,3-Dimethylbutene can also react with diazoacetate, denitrogenation and cyclization are carried out under the catalysis of copper to generate ester, and acid (or salt) is generated after hydrolysis.