Can asus k450vc be retrofitted with an SSD

Laptops are different from desktops after all, we recommend that you don't modify SSDs randomly, if there is a problem, it may lead to damage to the motherboard, so please consider carefully.

First of all, there are two locations on your motherboard that have SATA ports, one is the original hard drive location and the other is the optical drive location. If you want to add an SSD to the optical drive bay, you'll also need an optical drive bay, both 12.5MM and 9.5MM. The SSD specs are the same size.