Explain the concept of soft drug with an example

Explaining the concept of soft drug in relation to an example is as follows:

Soft drug (soft drug) refers to a class of drugs that have a specific activity that produces therapeutic effects, but the metabolites are not detectable outside the body or can only be detected in very low concentrations. Such drugs have a short duration of action in the body, causing less damage to the organism and reducing the incidence of adverse drug reactions.

To illustrate the concept of soft drugs with an example: a person with feverish symptoms due to a cold is prescribed an antipyretic and analgesic by his doctor. The drug works by lowering the body temperature and relieving pain while causing less irritation to the gastric mucosa. This drug is a soft drug, because it acts in the body for a short period of time, and does not cause greater side effects and harm to the human body.

The mechanism of action of soft drugs is similar to that of regular drugs, but the metabolism process in the body is different. Soft drugs are usually rapidly metabolized to inactive substances in the body or excreted in an inactive form, so that metabolites cannot be detected in the body or can only be detected in very low concentrations. The design and preparation of such drugs requires specific chemical modifications and alterations to ensure their stability in vitro and in vivo and to produce appropriate biological activity.

Another feature that distinguishes the concept of soft drugs from conventional drugs is the shorter duration of action in the body. Such drugs can quickly enter the circulation and be eliminated from the body, thus requiring multiple administrations to maintain the therapeutic effect in patients who need long-term medication. In addition, due to the shorter duration of action of soft drugs, it is also less stimulating to the body's own immune system, so it can effectively reduce the incidence of adverse drug reactions.

In summary, soft drugs refer to a class of drugs that have specific activity and are capable of producing therapeutic effects, but whose metabolites are undetectable or only detectable in very low concentrations outside the body. This type of drug has a short duration of action in the body, causing less damage to the organism and reducing the incidence of adverse drug reactions.