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Treatment of psoriasis (psoriasis) of traditional Chinese medicine topical formula?

Two, Chinese medicine treatment

Chinese medicine has a long history in the treatment of psoriasis, and in recent years, on the basis of inheritance and development, it has summarized a number of proven topical therapies and formulas for the treatment of psoriasis. Among them, ointment is the main one, tincture, fumigation and rubbing solution is the second one, and there are also methods such as acupuncture and acupoint injection.

2.1 Ointment

Since the Jin Dynasty "Liu Juanzi ghost legacy formula" pioneered the mercury treatment of ringworm, later generations of medical practitioners to treat this disease more heavy metal drugs as the main ingredient.

Lu [1] and others used light powder, mercury, big maple seed, wood turtle seed kernel, ice slice equal parts, and appropriate amount of sesame oil to apply the enemy silver ointment to treat 21 cases of psoriasis, and the result was cured in 16 cases, with a total effective rate of 95.2%.

Wang [2] used Qingdai, calcined clam powder, calcined gypsum, cedar powder, light powder, sesame oil, etc. to treat 51 cases of psoriasis patients, and 42 cases were cured, with a total effective rate of 96.1%. However, because of the liver and kidney toxicity of the mercury preparation in it limits its application in the clinic.

Seven hospitals in Shanghai [3] used tretinoin lactone alcohol ointment to treat 303 cases of this disease with a total effective rate of 85%.

Wang [4] treated 100 cases of psoriasis with compound hippocampus alkaloid ointment, of which 64 cases were cured, with a total effective rate of 99%.

Zhang's [5] et al. treated 36 cases of psoriasis with compound cynoderma ointment homemade by using cynoderma, cypress, gypsum plus petroleum jelly.

Zhong [6] and others used licorice flowing ointment to treat psoriasis, the cure rate of 68%, the effective rate of 100%, achieved better efficacy.

Guo's [7] used expectorant silver cream (containing 150 ml of extracts of Panax quinquefolium, licorice, serpentine and other medicines, 20 ml of nitrogen ketone, 150 g of urea, nipagin has been ester 1 g, plus cream matrix to 100 g) externally for the treatment of psoriasis in 72 cases, 40 cases were cured, with an overall effective rate of 90.3%.

Liu's [8] with the town silver cream (Zhimu, Huanglian, white fresh skin, fresh pepper, Qingdai, hawthorn, rhizoma Chuanxiong, licorice, etc. with vegetable oil frying until burnt black, remove the slag, and then add the powder of oxalic acid and musk, concentrated into a paste) externally coated lesions, and then polyethylene film sealing package, every 5 days for a change of medication, 2 months 1 course of treatment. *** treatment of psoriasis patients 703 cases, cured 669 cases, the total effective rate of 99.7%.

Niu's[9] ointment made of musk, black soybean oil, raw ground elm, cypress, dictyostelium, scutellaria baicalensis, bitter ginseng, and shengdi as the main ingredients, externally applied to the lesions and sealed with a polyethylene film, changing the medication every 5 days and buckling and beating with prunella needles for 30-50 days for a course of treatment. *** Treatment of psoriasis patients 145 cases, cured 138 cases, the total effective rate of 99.28%, better than 1% anthralin ointment control group.

Wang's [10] used Yinling ointment (Scutellaria baicalensis, Diels-Alder, Cyperus rotundus and other extracts of 39g, 59g, 29g, made into a powder, pure mustard gas 0.05g dissolved in glycerol, formulated as a 5-10-fold dilution of Vaseline 1000g) externally coated lesions, once a day, ****treatment of 675 cases, 409 cases cured, 203 cases improved, the total effective rate of 90.7%, 1-year Recurrence rate of 43%, efficacy is better than mustard gas ointment.

Du's [11] and other use of Zhenyin paste (mainly white fresh skin, Huanglian, pepper, Zhimu, sesame oil and other components and made by the traditional process of oil ointment) external coating lesions, after the polyethylene plastic film seal, 5 days to change the medication once a month for two months a course of treatment. ***Observation of 105 cases of treatment of psoriasis, cured 87 cases, the total effective rate of 100%.

Zhang's [12] et al. with Pulian paste (1 part of the end of scutellaria, 1 part of the end of cypress, 8 parts of petroleum jelly) uniformly coated in the skin lesions, 2 times a day, for the treatment of psoriasis in the progressive stage or the blood-heat type, and 5% boric acid ointment as a control, and at the same time orally cool the blood to clear heat and detoxification of traditional Chinese medicine broths, after 3 weeks, the treatment group of 37 cases of apparent effect of 10 cases, the total effective rate of 89.19%, significantly better than the control group, and there is no The total effective rate was 89.19%, which was significantly better than the control group, and there were no obvious adverse reactions.