Traditional Culture Encyclopedia - Traditional festivals - Under what circumstances will a gene mutation occur?

Under what circumstances will a gene mutation occur?

The factors leading to gene mutation are physical factors, chemical factors and biological factors. Physical factors include various rays, such as X-rays and ultraviolet rays. Chemical factors: nitrite, nitrite, base analogues, etc. (common in pickled products and barbecue products) Biological factors: some viruses.

Gene mutation is a sudden and heritable mutation of genomic DNA molecules. From the molecular level, gene mutation refers to the change of base pair composition or arrangement order of genes in structure. Although genes are very stable and can accurately replicate themselves during cell division, this stability is relative. Under certain conditions, a gene can suddenly change from the original existing form to another new existing form, that is, a new gene suddenly appears at a site to replace the original gene, which is called a mutant gene. Therefore, new traits that ancestors never had suddenly appeared in the performance of future generations.

Changes of genetic structure in 1 gene. Also known as point mutation, it usually causes some phenotypic changes. Mutations in a broad sense include chromosomal aberrations. Mutation in a narrow sense refers to variation. In fact, the boundary between distortion and point mutation is not clear, especially for fine distortion. Wild-type genes become mutant genes through mutation. The term mutant refers to both mutant genes and individuals with such mutant genes.

Gene mutation can occur at any stage of development, usually in the period of DNA replication, that is, the interval of cell division, including mitosis and meiosis; At the same time, gene mutation is related to DNA replication, DNA damage repair, canceration and aging. Gene mutation is also one of the important factors in biological evolution, so the study of gene mutation has a wide range of biological significance besides its own theoretical significance. Gene mutation provides mutants for genetic research and materials for breeding, so it is also of practical significance in scientific research and production.