What is chitosan?

Question 1: What is chitosan Chitosan, also known as chitin, chitosan, touching the butyl, is a natural aminopolysaccharide polymer substances, molecular formula (C8H13NO5)N, molecular weight in about one million, the chemical name is (1,4) poly-2-acetylamino-2-deoxy-D-glucan, stable, with good biodegradability and compatibility, very low toxicity ( LD50 16g/kg) and is widely available. It is a rare positively charged fiber structure compound in nature, insoluble in water, in acidic aqueous solution to produce hydration and gradually dissolved to form spherical capsule, pH increases when the transformation to linear, while the viscosity increases, can be dissolved in concentrated hydrochloric acid, sulfuric acid, nitric acid, cleavage occurs, the degree of polymerization decreases, such as in concentrated hydrochloric acid heated to 100 degrees Celsius can be decomposed into D-amino glucose in concentrated sulfuric acid can be produced sulfonic esterification reaction, to get heparin-like effect. In concentrated sulfuric acid, it can produce sulfonate esterification reaction and get heparin-like effect substance, and with concentrated nitric acid, it can produce nitrocellulose. Insoluble in dilute alkali, in concentrated alkali (> 40% sodium hydroxide or potassium hydroxide) heating can make the molecular acetyl stripped 65%-95%. Insoluble in chloroform, ethanol, etc., soluble in concentrated HAC, formic acid, lithic acid, etc.. The physical and chemical properties (solubility, molecular weight, acetyl content, specific spin, viscosity) of the product vary with different raw materials and preparation methods. Chitin in shrimp, crab, lobster carapace in high content (about 10% -30%), which is 1000-2000 1,4-linked-2-acetamido-2-deoxy-D-glucose (C8H13NO5) N direct polymer, molecular weight of 1-2 million, N2 content of 6.3% -6.7%.

Question 2: What is chitosan? Chitosan is a product of chitosan after deacetylation reaction, the degree of deacetylation (D.D) determines the amount of amine groups (NH2) content on the macromolecular chain, and D.D increase, due to the amine group protonation and make chitosan in dilute acid solution with more charged groups, the polyelectrolyte charge density increases, which will lead to the result will lead to changes in its structure, nature and properties, so far, chitosan dilute solution nature studies have ignored D.D., the research of the nature of chitosan, the polymer is a very important part of the polymer. So far the studies on the properties of chitosan in dilute solution have neglected the effect of D.D value on the equations.VANDUM et al. have studied the effect of different ionic strengths on the molecular size and viscosity of chitosan in dilute solution. The results concluded that different ionic strengths change the expansion of random nematic groups and hence the molecular size and the characteristic viscosity.The constants of the MARK-HOUWINK equation were determined for different D.D chitosan, and the results showed that the values of K,A varied with the value of D.D. The results showed that the K,A values varied with the value of D.D. The results showed that the K,A values varied with the value of D.D. The results showed that the K,A values varied with the D.D value. Thus, the constants K,A of the MARK-HOUWINK equation depend regularly on the degree of deacetylation of chitosan, and at the same molecular weight, the molecular size, characteristic viscosity and dilatancy factor of chitosan in dilute solution increase with the increase of the degree of deacetylation, while the characteristic ratio and the spatial resistance factor decrease with the increase of the degree of deacetylation. Thus, the average molecular weight of any chitosan sample within the applicable range can be calculated by a relatively simple measurement of the characteristic viscosity, and some basic data can be accumulated for further research. Since chitosan and chitosan are highly reactive and can be easily modified by a number of chemical reagents, much research has been carried out in this area and promising results have been obtained. Thus, chitosan has been modified by various methods. Alkylated CHITIN fibers have been successfully prepared abroad by a simple step of frozen sodium hydroxide-sodium dodecyl sulfate system. Alkylation produces a variety of alkyl halogen compounds with different chain lengths and bulk capacities, and the increase in affinity for water or formic acid is due to the disruption of part of the molecular crystal structure. NMR*** vibration studies have shown that the hydroxyl group at the C6 position is preferentially substituted at the C3 position. Alkyl-CHITIN fibers and films were also prepared. This improvement of the affinity property is of good value for future chitosan applications. In addition, chitosan porous beads were prepared, which have chelating effect on heavy metals and can also be used for immobilization reaction of biomaterials. Chitosan graft*** polymers were prepared by iodination and halogenation. The halogenation and iodination methods are mainly used for the modification of chitosan functional groups, in which iodination is mild and can produce precursors for various reactions. The reaction is easily carried out at the C6 position and is also used for the preparation of cationic graft*** polymers. The reaction is carried out at room temperature and under UV light at 308 NM. The modification of various functional groups of chitosan also includes the preparation of hydroxychitosan. At present, chitosan-based chitosan gels LCM-X (LCM1, LCM2) were prepared in China using formaldehyde and acetic anhydride as cross-linking agents. And their properties were investigated. There are few reports on the research and application of chitosan gels in China and abroad. This thesis explores this issue. The prepared LCM-X is neither soluble in water, dilute acid and alkali solutions, nor in general organic solvents, but LCM-X is a gel with reactive group (NH2), and has excellent properties such as good mechanical strength and chemical stability, and does not need any special treatment, that is, it has a reactive group (NH2), as well as its parent chitosan is rich in resources and inexpensive, which makes it a biopolymer of great potential for application. It is a promising biopolymer. However, the application of LCM-X is limited because no suitable dispersant has been found yet, resulting in the failure of LCM-X to form granular products. This point needs to be solved by further research. Domestic and foreign research on hydrogel is very important, the development of new hydrogel resources is one of the main tasks, hydrogel has excellent biocompatibility, anticoagulant, water absorption and swelling and good optical properties. Hydrogels are important in the research of immobilized enzymes, cell separation, protein preparation, slow-release drugs, manufacturing of contact spins and artificial organs. However, there are detailed reports on the properties of chitosan hydrogels at home and abroad, and only the preliminary properties of hydrogels have been explored in China, and it is concluded that the swelling of hydrogels is the strongest with methanol as the gel-forming medium, and the degree of cross-linking is inversely proportional to the RV value of chitosan hydrogels. Further studies on chitosan gels are needed.　　Chitosan's biocompatibility is good, in biomedical and pharmaceutical applications are extremely wide, can be used as burn dressings and wound healing agents, bandage gauze with chitosan treatment, wound healing speed can be increased by 75%. Chitosan made of absorbable surgical sutures, high mechanical strength, can be stored for a long time, can be used often ...... >>

Question 3: What are the functions of chitosan? Chitosan biocompatibility is good, in biomedical and pharmaceutical applications are extremely wide, can be used as a burn dressing and wound healing agent, bandage gauze with chitosan treatment, wound healing speed can be increased by 75%. Absorbable surgical sutures made of chitosan, high mechanical strength, long-term storage, can be sterilized by conventional methods, can be dyed, can be mixed with pharmaceuticals, can be degraded and absorbed by the organization, exempting patients from the pain of dismantling the thread. Chitosan can inhibit gastric acid and ulcers, and has the effect of degrading cholesterol and triglycerides. Heparin is an extremely effective anticoagulant with sulfonic acid and carboxylic acid groups. Sulfated chitosan is structurally similar to heparin, and such heparin-like derivatives generally have comparable or even surpassing heparin activity, which provides an effective way to provide synthetic and cheap anticoagulants. In addition, chitosan can be used to make artificial kidney dialysis membranes and contact lenses. Microcapsules prepared from chitosan, a biodegradable polymer membrane material, is an excellent and very promising medical slow-release system

In addition, chitosan can be used as a cling film on food. Its aqueous solution coated on the surface of fruits and vegetables, can be artificially formed on the surface of fruits and vegetables in a low-oxygen high carbon dioxide closed environment, inhibit the respiration of fruits and vegetables, while inhibiting the propagation of bacteria, improve the gloss of fruits and vegetables, and improve the organoleptic quality of fruit trees.

Question 4: What is the efficacy of chitosan? Give you an introduction to the chitosan of David's Chitosan, other than we do not understand, not nonsense.

Product Description:

Chitosan can impede the digestion and absorption of lipids, promote the conversion of cholesterol, increase HDL and LDL, increase the transfer of cholesterol from peripheral tissues to the liver, and effectively reduce cholesterol concentrations. The activity of insulin is related to the PH value in human body, if the PH value rises by 0.1, the activity of insulin rises by 30%. Chitosan can effectively regulate the acid-base balance in the body and improve the activity of insulin; at the same time, chitosan can also regulate the endocrine system, so that insulin secretion is normal, thus playing a role in lowering blood sugar.

Product Description:

Chitosan capsules have the functions of strengthening immunity, inhibiting aging, preventing diseases, promoting healing, and regulating human physiological functions.

Chitosan is the sixth element of life after protein, fat, sugar, vitamins, minerals and other nutrients.

Three adjustments: immune regulation, PH regulation, endocrine regulation

Clinical experiments have shown that chitosan can enhance phagocytosis, natural killer cells (NK cells), cytokine-activated cells (LAK cells) activity, promote the generation of interleukin Ⅰ, Ⅱ, and increase the content of serum hemolysin. Regulate the acid-base balance of the human body, regulate the non-healthy acidic body into a weak alkaline healthy state. Regulate the vegetative nervous system and endocrine system, promote the secretion of male and female hormones, so as to enhance the vitality of the body, restore youth and delay aging. Three rows: exclude harmful cholesterol, exclude heavy metals, exclude toxins in the body Miraculous "electric powder" can adsorb toxins and harmful heavy metal ions with the metabolism out of the body. Especially for children's lead poisoning, pesticide pollution of fruits and vegetables, has a preventive effect. Three lower: lowering blood lipids, lowering blood sugar, lowering blood pressure

Chitosan can impede the digestion and absorption of lipids, promote the transformation of cholesterol, elevate high-density lipoproteins and reduce low-density lipoproteins, increase the transfer of cholesterol from peripheral tissues to the liver, and effectively reduce cholesterol concentrations. The activity of insulin is related to the PH value in human body, if the PH value rises by 0.1, the activity of insulin rises by 30%. Chitosan can effectively regulate the acid-base balance in the body and improve the activity of insulin; at the same time, chitosan can also regulate the endocrine system, so that the secretion of insulin is normal, which can play a role in lowering blood sugar.

Modern medical research suggests that elevated blood pressure is related to elevated chloride ion content in the human body. After chitosan is decomposed, the basic unit of chitosan can be combined with chloride ions and discharged from the body, so that the level of chloride ions in the body is reduced, so that the formation of angiotensin Ⅱ is reduced, the body of bradykinin is increased, and the blood vessel is expanded, which can reduce the role of blood pressure. And chitosan can alleviate the side effects of western medicines for lowering blood pressure, strengthen the other effects, and play a synergistic role.

Three inhibitions: inhibit cancer cells to prevent cancer recurrence, inhibit cancer metastasis, inhibit cancer toxins

The surface charge of normal cells without cancer is in dynamic balance, while the surface of non-normal cells with cancer has a more negative charge, resulting in an imbalance of cell surface charge, which decreases the adhesion between cells and destroys the tissues. Chitosan is a positively charged cation group, which can be adsorbed to the surface of cancerous cells and neutralize the charge, thus inhibiting the growth of cancerous cells. Chitosan has the property of adhering to the adhesion molecules on the surface of vascular endothelial cells, which can block the adhesion and movement of tumor cells to vascular endothelial cells and inhibit the generation of capillary endothelial cells in cancerous tissues, preventing cancerous tissues from spreading to the surrounding area, and thus inhibiting and preventing the expansion and metastasis of tumors.

Clinical efficacy of David's Chitosan

(a) Prevention and treatment of cardiovascular and cerebrovascular diseases The therapeutic mechanism of chitosan is to activate vascular cells, restore the elasticity of blood vessels, and repair the broken blood vessel wall; it can also effectively reduce blood viscosity and accelerate blood circulation. Regulate blood lipids and blood pressure

(2) Inhibit the activity of cancer cells and prevent cancer cells from spreading and metastasis

1. Enhance the immunity of human body comprehensively;

2. Eliminate the supply of nutrients to the cancer cells;

3. Reduce the acidic wastes produced by the metabolism of cancer cells;

4. Reduce the release of enzymes from the cancer cells to the surrounding.

(3) Regulate blood sugar

1, Chitosan can promote insulin secretion from pancreatic β-cells;

2, Chitosan can regulate PH to weak alkaline, improve the utilization rate of insulin;

3, Chitosan can activate the liver function and ensure glycogen reserve.

(D) Liver protection

Chitosan can activate liver function and enhance the vitality of aldehyde dehydrogenase. It has good effect on acute and chronic hepatitis, alcoholic liver, and can prevent cirrhosis. Can promote the production of hepatitis virus antibodies, improve the efficacy ...... >>

Question 5: What is chitosan? It is a chitin processing product, is a commonly used food additives

With some physiological activity, play some health effects

Question 6: What is chitosan, what is the effect Chitosan is a product of chitin by the reaction of deacetylation, is the only positively charged alkaline polysaccharides found in nature, but also a cationic natural polymer containing amines Animal food fiber, with the regulation of the body's acid-base balance, nutrition, activation, repair of cells, enhance the body's self-healing power, can be adsorbed and discharged from the body of a variety of pathogenic substances.

Question 7: What are the ingredients of chitosan? Which brand is better Chitosan is a chitin degradation, from the shrimp and crab shell or head and feet, on the human body to reduce three high and liver protection is very helpful, brand, there are a lot of, I'm taking is the blue bay, because this brand of chitosan deacetylation of the high degree of quality is also good, although the price is not very low, but the effect is really very good, the money is also expensive expensive life ah 、、、、

Question 8: chitosan has a What is the effect? Which brand is good Chitosan is a natural polymer animal food fiber, has a strong adsorption capacity, can adsorb toxins in the body, excess fat sugar, etc., can assist in the regulation of high blood lipids, high blood pressure, high blood sugar and gout, chitosan quality standards to see its degree of deacetylation, the higher the degree of deacetylation of the higher the quality of the better, there is an enterprise in Fujian blue l bay technology to do the quality of chitosan is good.