Is the spice trade profitable in history?

First of all, why do businessmen in history love spices so much? Love is because it is profitable, whether it is an Arab businessman, a Venetian businessman or a Genoese businessman. Of course, spice dealers may not only do spice business, but also profitable goods may be added to their trade list; ?

Secondly, what are spices for? -Seasoning, perfuming, medicinal use, aphrodisiac, sacrifice, criticism, showing off wealth, etc. The concept of spices has a wide range of meanings, not only edible spices are called spices, but also their connotations are different in different periods and places. ?

Third, why don't Europeans grow them themselves? -because from the geographical conditions, some spices are not suitable for planting in them; Some spices may need to be imported because of large demand and low output; The same applies to China.