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Bee therapy for stroke

The therapeutic effect of bee venom and royal jelly on post-stroke is directly related to the complex chemical components they contain, and their mechanism of action is mainly the result of the combined effect of the wide range of biological effects and biological effects of these chemical components. Stroke is a difficult disease, especially the sequelae of stroke, and there is no ideal effect of Chinese and Western medical treatment. The use of bee therapy brings hope to the recovery of stroke patients.

1, break through the blood-brain barrier to play a therapeutic effect

Due to the role of phospholipase A2, bee venom peptide contained in the bee venom, the bee venom can be exempted from overcoming the blood-brain barrier, contact with the focal point of the part of the disease, resulting in a good therapeutic effect. Phospholipase A2 contained in bee venom is a neurotoxin with presynaptic effect, which can selectively change the process of acetylcholine release from nerve endings of vertebrates. The toxicity of bee venom to central and peripheral nerves has been reported in numerous studies. Zhou Shao-ci (1980) experimentally confirmed that bee venom has a significant effect on the electrical activity of peripheral and central nervous systems, emphasizing the neurotoxic activity of bee venom phospholipase and its possible role in destroying the blood-brain barrier. For example, the bee venom peptide in bee venom can act directly on the central nervous system through the blood-brain barrier. Many clinical cases of using bee venom to treat the sequelae of stroke have shown that the active ingredient of bee venom breaks through the limitations of the blood-brain barrier and then contacts the lesion to change the lesion in order to restore the patient's health.

Medical practice has shown that there is a system around the central nervous system that restricts the exchange of substances between the blood and the brain, and this system is called the "blood-brain barrier". Scientists have observed that when injecting dye into a vein, the dye that goes back into the bloodstream stains all the tissues of the body but not the brain. This property of the blood-brain barrier prevents many substances that are beneficial to the stroke site, such as drugs that dissolve emboli, from reaching the brain. This determines that patients with cerebrovascular disease are not well treated by conventional routes of administration, such as oral and intravenous, sometimes to the point of helplessness. This is because orally administered drugs must first pass through the human digestive system and then enter the blood circulation system, during which time they must be partially eliminated by the human metabolism. As the drug flows through the body with the blood, it is partially absorbed by the relevant organs, and ultimately approaches the brain tissue around about 20% of the total dose. Due to the obstruction of the blood-brain barrier, even if it enters the brain tissue, it does not necessarily reach the site of the lesion, so the drug that can play a role in the efficacy of the drug is minimal. This is one of the main reasons why the effect of pure drug therapy is unsatisfactory during the recovery period and the treatment of sequelae in stroke patients.

The existence of the blood-brain barrier is physiologically important for maintaining a stable chemical environment around the brain tissue and preventing harmful substances in the blood from invading the brain. In some parts of the brain, such as the periventricular organs around the third ventricle of the hypothalamus and the posterior border of the medulla oblongata, the blood-brain barrier is relatively weak, and the permeability of capillaries to many substances is higher than in other parts of the brain. Therefore, certain substances in the blood loop, such as angiotensin II and other peptides, can enter the brain in these parts and act on the corresponding receptors, causing various effects. Bee venom is a treasure trove of peptides, and a variety of active peptides have been found, which is the main reason why bee venom can pass the blood-brain barrier. Bee venom peptide is the main active substance of bee venom, accounting for 75% of dried bee venom, with direct and indirect hemolytic effect. Among them, bee venom peptide I consists of 26 amino acids, bee venom peptide II consists of 27 amino acids, both of which have hemolytic and other biological activities; bee venom ming peptide consists of 18 amino acids; and anitoxin peptide consists of 103 amino acids. Because of the high permeability of amino acids and glucose, the bee venom solution can pass the blood-brain barrier, which has ideal effect on the after-effects of stroke in the brain.

2. Bee venom runs through the meridians and reaches the lesion site

Conventional treatment of cerebral thrombosis and cerebral embolism is to run the embolism-dissolving drugs along with the blood to reach the lesion site to achieve the purpose of dissolving the embolism and eliminating the embolism foci. In fact, when the cerebral blood vessels are completely blocked or occluded, the blood flow has been blocked, and the drugs in the blood cannot approach the lesion to dissolve the embolus. Even if the drug is used, its purpose is to improve cerebral blood circulation and cerebral blood supply through the formation of collateral gyrus and to reduce brain tissue damage. If thrombolytic therapy is used, it should be carried out under the guidance of experienced doctors, and generally it should be used for 6 hours after the onset of the disease, more than 12 hours, and then given thrombolytic therapy, there is a danger of causing bleeding in the embolized part of the body, and if it is not good to grasp the indications and contraindications, it can worsen the condition, and even jeopardize the life. Therefore, drug therapy is difficult to reopen the occluded blood vessels, it is difficult to recommunicate.

Bee-needle therapy is actually bee venom through the human body acupuncture points, into the meridian system to run to the lesion site, and the traditional drugs in the body to run a different route, walking is not a road. Clinical practice has proved that: according to the various symptoms of post-stroke syndrome, after taking bee stings through the meridians and stimulating the skin, the amplitude of local vascular tolerance pulse fluctuation is significantly increased, and its therapeutic effect is related to the improvement of the blood back to the circle. The stimulation of the skin will inevitably stimulate the functional activity of the skin's collaterals, and through the meridian connection and infusion effect, the qi and blood flow from the surface to the inside will be unimpeded, so that the patient's blood circulation will be improved, the metabolism of the function will be vigorous, the stasis of blood will be dissipated, and the pathogenic substances will be reduced, and the disease-suppressing and anti-inflammatory substances will be increased, so that the symptoms of the affected area will be alleviated or disappeared, and that is the difference between the bee-needle therapy and the traditional medicines. Bee sting is beneficial to the therapeutic effect of post-stroke and shortens the healing time.

3. The effect of bee venom on blood and blood vessels

Stroke is caused by cerebrovascular pathology, which is directly related to the blood vessels and blood in the brain, so the effect of bee venom on blood vessels and blood is related to the efficacy of the bee sting in treating the after-effects of stroke. Experts' research confirms that bee venom has the effect of prolonging blood coagulation time and anti-thrombosis. Bee venom can significantly increase the fluidity of red blood cell membrane, significantly reduce plasma viscosity, accelerate the electrophoresis of cells again, and has the effect of activating blood circulation and removing blood stasis. Bee venom has the effect of lowering cholesterol, and can increase hemoglobin and reflexively promote blood circulation and material metabolism, so that the body function is normalized. Bee venom is effective in the treatment of blood stasis associated with thrombosis and hyperviscosity.

Bee venom can cause vasodilation, and has a significant effect on lowering blood pressure. Its effect on blood vessels is similar to histamine, which can cause vasodilatation and blood pressure drop. A large number of data show that bee venom has broad-spectrum biological activity on the microcirculatory system, a very small amount of bee venom into the body can change the functional state of the capillaries. When using bee needling to treat diseases, it firstly affects the microcirculation blood vessels, and the influence on microcirculation, mainly its morphology, flow state and peripapillary state are changed to different degrees. Bee-needle therapy can speed up blood flow, improve red blood cell aggregation, increase microvessel opening, and promote exudation and hemorrhage absorption, thus improving the abnormal state of input branch, output branch, and micro thrombus; it is conducive to the improvement of microcirculation of tissues, and promotes the perfusion of capillaries, which is beneficial to the utilization of oxygen by tissues. Bee venom on the vascular microcirculation changes include platelet aggregation and changes in the state of the coagulation system. On the vascular wall itself is mainly permeability and diastolic response changes.

4, bee therapy has the role of both symptoms and root causes

The use of bee stings or at the same time let the patient take royal jelly to treat the sequelae of stroke, not only can effectively treat the sequelae of stroke, but also prevent recurrent cerebral hemorrhage and other conditions. This is due to the fact that bee therapy generally has the effect of treating multiple diseases at the same time and treating both symptoms and root causes. That is, the use of bee therapy to treat a certain disease at the same time, some other diseases can also be prevented and treated at the same time.

In the cerebral arteriosclerosis and hypertension on the basis of the formation of intracerebral micro-aneurysm aneurysm wall, once the body can not withstand the rise in blood pressure and rupture, resulting in intracerebral hemorrhage is a critical disease. Patients with cerebral hemorrhage have an important characteristic: the recurrence rate of cerebral hemorrhage within 10 years of the first cerebral hemorrhage is the highest, and patients with recurrent cerebral hemorrhage after 10 years are not uncommon. Recurrent cerebral hemorrhage damages brain tissues more seriously, the brain's self-repair ability is worse, and its disability and death rates are higher. Bee-needle therapy can be utilized to treat the sequelae of stroke and at the same time, it can also treat hypertension, arteriosclerosis and other conditions that cause stroke at the same time. Especially after the cerebral stroke is cured, continue to patients with bee needle therapy, and let the patient take royal jelly and honey, on the one hand, consolidate the efficacy of the treatment so that the body will soon recover, and secondly, it is also an effective measure to prevent the recurrence of cerebral hemorrhage.

After the first cerebral hemorrhage, traditional medicine often pays attention to the symptomatic treatment of the patient, relaxing the prevention and treatment of cerebral hemorrhage recurrence, causing the first cerebral hemorrhage of the original hypertension, atherosclerosis, hyperlipidemia, hyperviscosity and diabetes mellitus and other causative factors can not continue to be treated and completely eliminated, hypertension and cerebral atherosclerosis and other pathological processes are still progressing, and once the time is ripe, it will naturally cause the recurrence of cerebral hemorrhage. Cerebral hemorrhage recurrence. By utilizing bee-needle therapy or supplementing it with honey, royal jelly and other bee products and continuing to consolidate the treatment, it is possible to prevent the recurrence of the disease after the treatment of cerebral hemorrhage. This is due to the fact that bee therapy has the characteristics of treating multiple diseases together and treating both symptoms and root causes. The indications for bee-needle therapy include conditions that cause stroke, such as the treatment of hypertension, arteriosclerosis, diabetes and hyperviscosity. The indications for royal jelly therapy include hyperlipidemia, arteriosclerosis, diabetes and hypertension.

In the bee products are characterized by both symptomatic and therapeutic. Royal jelly, for example, has an adjusting effect on the cardiovascular system. Clinical practice has proved: the use of royal jelly and can treat hyperlipidemia, thrombosis and hypertension, etc., the efficacy is remarkable. Royal jelly in the niacin can make blood vessels dilated, acetylcholine to increase arterial blood flow, both can obviously play a role in lowering blood pressure; royal jelly on the human body blood pressure has a bidirectional regulation function, when the blood pressure is lower than the normal value of the royal plasma plays a role in elevating the role of high blood pressure, when the blood pressure is higher than the normal value of the royal plasma can lower the blood pressure; so that the human body blood pressure is always in the normal range. Royal jelly can reduce blood fat and cholesterol through the regulation of fat metabolism. After the phospholipids in royal jelly are absorbed into the blood by the small intestine, cholesterol and fat particles in the blood are reduced, and the cholesterol suspended in the blood is not deposited on the blood vessel wall, thus preventing atherosclerosis. Royal jelly has the effect of activating blood circulation and removing blood stasis, which can improve the high coagulation state of blood. Vitamin E in royal jelly can reduce plasma cholesterol, increase the elasticity of blood vessels, improve microcirculation in the body, and increase blood flow to the liver. Therefore, the treatment of certain diseases with royal jelly can be achieved with the treatment of multiple diseases and treat both symptoms and root causes.

Currently in the world of Chinese and Western medical profession there is no ideal special drugs for stroke, cardiovascular stroke sequelae of the treatment of drugs, but the bee venom contained in the phospholipase A2 titanium can break through the blood-brain barrier to play a special effect. Bee therapy generally has a multi-disease treatment, the role of both symptoms and root causes. That is to say, the use of bee therapy to treat a certain disease at the same time, some other diseases can also be prevented and treated at the same time. Clinical experiments have proved that when the use of bee therapy no longer needles and medicines can be used to bring recovery to patients with cerebral infarction (stroke).