Laboratory meningitis diagnosis sampling gold standard is

Hemogram: The number of white blood cells is obviously increased, the highest is 40× 109/l, and neutrophils are above 80%-90%.

Lumbar puncture should be performed for patients suspected of meningitis. The pressure of cerebrospinal fluid (cs) often increases, as high as 65438±0.96 kpa. The appearance of typical cases of cs is turbid like rice soup, and even pus. The number of white blood cells increased to hundreds of millions per liter, mainly polymorphonuclear cells; Protein increased significantly, reaching1-5g/l; The sugar content is often lower than 2.22mmol/l, and the chloride is also slightly reduced. Gram-negative diplococcus can be found in neutrophils by cs smear.

Meningitis separated from the patient's cs or acute blood.

Detection of meningococcal group-specific polysaccharide antigen from serum or urine or cs of patients in acute stage.

The serum antibody titer of convalescent patients is 4 times or more than 4 times higher than that of acute patients.

The specific dna fragment of epidemic cerebrospinal meningitis in serum or cerebrospinal fluid of patients with acute phase was detected by pcr.