Traditional Culture Encyclopedia - Traditional virtues - The following drugs are non-narcotic analgesics
The following drugs are non-narcotic analgesics
As for why the answer is pentazocine, it can be explained as follows:
Narcotic analgesics mainly refer to opioid receptors. At present, there are μ, γ and K receptors. The main pharmacological effects of opioids, such as analgesia, sedation, respiratory inhibition, pupil contraction, euphoria and dependence, are mainly mediated by μ receptors!
Pethidine, morphine, fentanyl and methadone are all opioid receptor agonists, which mainly act on μ opioid receptors and are addictive, so they belong to narcotic analgesics and belong to anesthetics in pharmaceutical administration!
On the other hand, pentazoxazine is a partial agonist of opioid receptors. Its analgesic effect is to stimulate opioid K receptor and antagonize opioid μ receptor, so it is less addictive. Pentazosin is classified as a non-narcotic drug in administration.
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