What is the meaning of drug sensitivity and drug resistance?

Resistance, also known as drug resistance, refers to the tolerance of microorganisms, parasites, and tumor cells to the effects of chemotherapeutic drugs, and once resistance occurs, the chemotherapeutic effect of the drug is significantly reduced. Resistance can be categorized into acquired resistance and natural resistance according to the cause of its occurrence. Natural resistance can also exist in pathogens in nature, such as a particular strain of bacteria. When antibiotics are applied for a long period of time, the sensitive strains that make up the majority of the population are constantly being killed, and drug-resistant strains multiply, replacing the sensitive strains and increasing the rate of bacterial resistance to the drug. The reason is currently considered the latter way is the main reason for the production of drug-resistant bacteria. Pathogens resistant to a drug, for the structure of similar or the same nature of action of the drug can also show resistance, called cross-resistance (CrossResistance), according to the degree of difference, there are completely cross-resistant and partially cross-resistant points. With the increasing application of antibiotics, bacteria show different degrees of resistance to some commonly used drugs. For those drugs that have been used for a longer time and more widely used, the more serious the bacterial resistance tends to be. In order to maintain the effectiveness of antibiotics, attention should be paid to their rational use. Related Words for Drug Resistance, Cross-Resistance References