How to treat Helicobacter pylori infection with traditional Chinese medicine?

Since Australian scholars Warren and Marshall first discovered Helicobacter pylori (Hp) in 1983 and put forward that Hp is the pathogenic factor of chronic gastritis and peptic ulcer, scholars at home and abroad have made great progress in this field. In recent years, Chinese medicine has also made some achievements in the prevention and treatment of Hp infection, and its advantages have begun to appear.

(1) Single traditional Chinese medicine and Chinese patent medicine are sensitive to Notoginseng Radix and Cortex Magnolia Officinalis, moderately sensitive to Mume Fructus and Rhizoma Corydalis, and highly sensitive to Rhizoma Coptidis and Radix et Rhizoma Rhei. Dahuang tablets (0.25g per tablet, equivalent to 1g crude drug), 3 ~ 4 capsules, treated three times a day, the Hp negative rate was 36.9%; Single dandelion granule is used to treat 9 1 case of peptic ulcer, and the cure rate is 94.4%. Dandelion has a strong killing effect on Hp. 32 cases1case of gastropathy caused by helicobacter pylori were treated with areca nut. After two weeks, the clearance rate of Hp was 68.8%, and after four weeks to six months, the eradication rate was 62.5%. The cure rate of gastritis and ulcer in Hp negative cases was 95.5%. Brucea javanica oil emulsion is used to treat Hp-related gastropathy, and the negative rate of Hp is 49.5%, which shows that many single Chinese medicines have good anti-Hp infection effects.

In addition, according to the research, the curative effect of Sanjiu Weitai and Hericium erinaceus tablets on chronic gastritis may be related to their ability to inhibit and kill Hp.

(2) compound Chinese medicine treatment ① heat-clearing and detoxification method. Many scholars believe that drugs for clearing away heat and toxic materials can kill Hp. Commonly used drugs are dandelion, Scutellaria barbata, honeysuckle, forsythia, Hedyotis diffusa, Coptidis Rhizoma and so on. , but their compatibility is different.

② the method of strengthening body resistance and eliminating evil. Some scholars take strengthening the body resistance and eliminating pathogenic factors as the treatment principle, and treat Hp infection with astragalus root, codonopsis pilosula and other prescriptions plus heat-clearing and detoxification products. In addition, research by Kazuhiro Terada of Kagawa Medical University in Japan shows that Huanglian Jiedu Decoction, Banxia Xiexin Decoction, Sini Decoction, Liujunzi Decoction and Huanglian Decoction have good anti-Hp effects.

At present, although there are many reports on the treatment of Hp infection by traditional Chinese medicine, and some progress has been made, on the whole, the treatment of Hp infection by traditional Chinese medicine is still in the stage of clinical observation and clinical verification, and many research work is at a low level of repetition and low credibility. Therefore, in the future research work, it is necessary to conduct in-depth research from pathology, pharmacology and animal models to clarify the mechanism of action of traditional Chinese medicine and improve clinical efficacy.