Traditional Culture Encyclopedia - Traditional festivals - What are the conditions under which drugs are monitored?
What are the conditions under which drugs are monitored?
1, low therapeutic index, narrow safety range and strong toxic and side effects.
2. Drugs with nonlinear pharmacokinetic characteristics.
3. Drugs with great individual differences in the process of drugs in vivo.
4. There are dangerous drugs when poisoned or ineffective, such as anti-rejection drugs used after organ transplantation, such as cyclosporine, tacrolimus and other drugs that affect the survival of transplanted organs. Excessive dosage will cause adverse reactions.
5, need to use a drug for a long time.
6, need to use a variety of drugs.
7. Drugs with unconventional administration scheme: In some cases, doctors can adopt unconventional special administration scheme according to the patient's condition. For example, for cancer chemotherapy patients, sometimes you can try to use large doses of chemotherapy drugs. At this time, it is necessary to pay close attention to the patient's blood concentration to prevent serious toxic reactions.
8. Drugs with poisoning symptoms very similar to those of diseases.
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