Gastric ulcer or gastric erosion, which is more serious and more likely to become cancerous?

Peptic ulcer is a common digestive tract disease, which is mainly divided into gastric ulcer and duodenal ulcer. Most of them occur in esophagus, stomach or duodenum, but also in the vicinity of stomach-jejunum anastomosis or Meckel diverticulum containing gastric mucosa. Gastric ulcer and duodenal ulcer are caused by gastric acid and pepsin digesting mucosa itself. Gastric acid and pepsin are only one of the main causes of ulcer formation, and other causes can form peptic ulcer.

First, what diseases will gastric ulcer aggravate?

1. Upper gastrointestinal bleeding: According to statistics, among various causes of upper gastrointestinal bleeding, ulcer accounts for about 50%, ranking first. . Gastric ulcer bleeding is more than duodenal ulcer. Bleeding is easy to occur within 1 ~ 2 years after peptic ulcer appears.

2. Ulcer perforation: Peptic ulcer perforation can be divided into acute, subacute and chronic types. The incidence of duodenal ulcer is higher than that of gastric ulcer.

3. Pyloric obstruction: About 65,438+00% patients with peptic ulcer can be complicated with pyloric obstruction, which mostly occurs in duodenal ulcer, followed by pyloric canal's or pre-pyloric ulcer.

4. Canceration: Whether chronic gastric ulcer will become cancerous, gastrointestinal experts tell you that gastric ulcer canceration exists, and its canceration rate is estimated to be 1% ~ 7%. Canceration of gastric ulcer often occurs at the edge of ulcer.

2. Which is more serious, gastric erosion or gastric ulcer?

As can be seen from the following figure, the whole stomach wall is divided into four layers, namely, mucosa, submucosa, muscle and adventitia. The mucus layer is equivalent to the skin of our body, and the muscle layer is equivalent to the muscle layer under the skin of our body.

First of all, gastric erosion refers to superficial ulcers confined to the gastric mucosa. Its depth does not exceed the muscularis mucosa. Some people think that it is the early stage of gastric ulcer, but not all gastric erosion can develop into gastric ulcer.

Secondly, gastric ulcer is a kind of chronic ulcer located between cardia and pylorus, which mainly refers to the tissue damage outside the muscularis mucosa caused by the self-digestion of gastric digestive juice. Its typical clinical manifestations are pain and discomfort, fullness and belching, pantothenic acid or regular epigastric pain, and even melena and hematemesis.

There is a difference between gastric erosion and gastric ulcer. Gastric ulcer penetrates the muscularis mucosa and inevitably leaves fibrous scar after healing. The surface is covered with a layer of epithelium, and the muscularis mucosa cannot regenerate. Gastric erosion does not penetrate the muscularis mucosa, so there is no trace after healing. The most common causes of the two diseases include Helicobacter pylori infection, taking non-steroidal anti-inflammatory drugs (NSAID) and hypersecretion of gastric acid. In addition, they can also be caused by genetic factors and emotional fluctuations, overwork, irregular diet, long-term smoking, alcoholism and other factors.

If there are symptoms of gastrointestinal discomfort such as "stomach pain, bloating, acid regurgitation, heartburn, bitter taste, bad breath, belching and diarrhea", it is necessary to do gastrointestinal examination in time, early detection, early diagnosis and early treatment.